Introduction. Antimicrobial resistance is a serious global public health problem. 1 - use of antibiotics by humans, factories and farms, poor hygiene and sanitation, and ineffective infection prevention and control in health care settings are considered important reasons in the emergence and distribution of antibiotics. Sodium perborate solution can be used sustainably in Applications of antibiotic kanamycin for P. aeruginosa and their effects on the survival of bacteria in lake water and resistance to antibiotic kanamyin are studied. OBJECTIVE To study boron derivatives with MIC value, namely boric acid H 3 BO 3 Borax anhydrous Na 2 B 4 O 7, Objective The present study evaluated the antibacterial activity and mode of action of fibrauretin on Escherichia coli, E. coli and Staphylococcus aureus, and synergistic effect with kanamycin against multi-resistant E. coli. Results Fibrauretin exhibited an inhibitory effect on the growth of tested bacteria with a minimum of 2. Use of antibiotics in different countries in the EU region and the spread of resistance of E. coli. coli to antibiotics. It is absolutely clear to us today that the antibiotic resistance of E. coli and certain other bacteria involves a combination of different factors 87,88. Research results indicate that E. coli has the highest resistance to vancomycin and related glycopeptides which are drugs of last resort for the treatment of serious infections caused by Gram-positive bacteria such as Enterococcus species, Staphylococcus aureus and Clostridium difficile. Vancomycin has long been considered immune to resistance due to its bactericidal activity based on binding to the bacterial cell. Isolates of E. Uropathogenic coli were collected from several major hospitals in Tehran between May and. Bacterial isolates were identified as E. coli by a standard microbiological and biochemical method. Single colony growth with gt counts and ml colony forming units were considered positive urine cultures. All ; Introduction. Antimicrobial resistance is a serious global public health problem. 1 - use of antibiotics by humans, factories and farms, poor hygiene and sanitation, and ineffective infection prevention and control in health care settings are considered important reasons of the emergence and distribution of antibiotics. Therefore, all but one strain tested had MICs ≤4. mL 99 The results of this study show that green tea can have an antimicrobial effect on the E. coli bacteria responsible for urinary infections. 3. All these studies show that green tea has an antimicrobial effect on E. coli through different mechanisms.